Patients Show Strong Interest in Alzheimer’s Blood Tests

A new study published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association is shedding light on how patients feel about emerging Alzheimer’s blood tests — and the results may surprise you. In part one of our conversation, psychologist Andrea Russell, Ph.D., of the Northwestern University Feinberg School of Medicine, explains why interest in these tests is high, even though awareness is still low.

The survey, which included nearly 600 adults with an average age of 62, found that 84% had never heard of Alzheimer’s blood tests. Yet after a brief explanation, 85% said they would take one if their doctor recommended it. For Russell, this gap highlights a disconnect between what patients are hearing in the media and what they’re learning in clinical settings.

Understanding the Disconnect

Despite growing public attention around Alzheimer’s disease, many patients still lack clear, practical information about what these tests can (and cannot) do. Russell noted that fear and uncertainty often shape perceptions, especially given how Alzheimer’s is portrayed as a devastating, untreatable condition.

At the same time, she emphasized that patients are more nuanced in their thinking than we might expect. Many recognize that living with Alzheimer’s can still include meaning, purpose and quality of life. This balanced perspective may help explain why, when given accurate information, patients show a strong interest in testing.

What Patients Need to Know

A key takeaway from the study is that education matters. These blood tests are not diagnostic; they don’t definitively predict whether someone will develop Alzheimer’s. Instead, they identify biomarkers that may indicate increased risk and guide next steps, such as additional testing or monitoring.

Russell stressed the importance of setting realistic expectations:

• A positive or negative result is not a final answer.
• Testing should be part of a broader conversation with a health care provider.
• Patients need to understand what happens after the test, including follow-up care and support.

She also noted that decisions about testing are deeply personal. Factors like individual values, health goals and tolerance for uncertainty all play a role.

Balancing Anxiety and Empowerment

One of the most complex findings is the emotional impact of testing. Many patients anticipate distress if results suggest a higher risk. At the same time, Russell explained that having information, even difficult information, can sometimes bring relief and a sense of control.

For some, testing may reduce uncertainty and motivate positive lifestyle changes, such as improving diet, exercise and overall brain health. For others, it may increase anxiety, especially given the current limitations in treatment.

Russell emphasized that Alzheimer’s blood tests are not a one-size-fits-all solution. But as they become more widely available, ensuring patients have clear, balanced information will be critical. With the right context and support, these tools could help patients feel more informed, engaged and proactive in their health decisions.